The WRISK project regularly asks contributors to share their perspectives on a range of issues related to risk communication in pregnancy to further understanding of the challenges faced by scientists, clinicians, policy makers and of course women themselves when trying to navigate risk messaging. These represent individual and personal viewpoints and are aimed at encouraging reflection and discussion, rather than reaching conclusions. If you have an idea for a blog or a perspective you would like to share please do get in touch with the team.

Clare is a freelance writer, trainer and community manager who has worked for a number of charities including Mind, The Miscarriage Association and Action on Postpartum Psychosis. She blogs at and tweets @fostress.



Coming off antidepressants while trying to conceive?

In 2016 a GP recommended I come off my antidepressants (Citalopram and then Sertraline) while trying to conceive. With stories like this one in mind, I did my best. It was one of the worst three months of my life. I wrote about it here.

When I finally fought through the initial withdrawal symptoms I thought things would get easier. Instead they got harder. More chest pain. More tears, panic and anger. Suicidal thoughts. More running. More fighting my body.I was so stressed and exhausted my periods stopped.

It took three months to realise I couldn’t do it. That nothing was worth the destruction wreaked on my body, our health and our relationship. Another GP in the same practice told me I shouldn’t have stopped taking them. Additional stress can make it harder to conceive. This left me shaky, tearful and confused.  It had only been the certainty I was doing the ‘right’ thing that had kept me going. I thought I wasn’t myself on medication. Turns out it helps me be myself. Without it I was a dark anxious shadow. My world narrowed, anxieties bulged and took over. I retreated into myself and lost the strength or clarity of thought to control eating or exercise demons.

Almost as soon as I restarted Sertraline, my periods came back. Eight months later we got a positive pregnancy test for the first time. I’m not angry about the conflicting advice around stopping medication before we conceived. I think I had to go through it to help me feel comfortable in my decision to keep taking them through conception and any potential pregnancy.


Coming off anti depressants during pregnancy?

I’m more upset about the advice I received (and the almost flippant way it was given) when 17 weeks pregnant. In the meantime we had moved away from London and so it was another new GP who told me I should come off again. She told me that 50mg was a low enough dose to allow me to stop immediately or I could take it every other day for a couple of weeks and then stop. I told her that last time I tapered my dose for over two months and it didn’t prevent the horrible withdrawal symptoms. She seemed convinced the main reason I found it hard before was because I was anxious about trying to conceive. In the appointment time we had it was hard to explain that it was considerably more complicated than that. I did try but felt increasingly emotional and unsure of myself.


Mental health agendas vs. pregnancy agendas

When you are pregnant and also manage mental health problems you have lots of people telling you what to do. Different authorities often have slightly different agendas, follow different recommendations and suggest different things. It feels like an extra layer of disempowerment and it’s hard not to get caught between what’s best for your mental health and what’s recommended in pregnancy.

I have:

  • personal experience that strongly supports staying on antidepressants,
  • a well considered and discussed (with a doctor and my husband) decision to start taking them again,
  • an awareness of the power imbalance implicit in a doctor’s consulting room,
  • access to a lot of relevant research that emphasises the importance of maternal mental health and the danger for both mother and developing baby of coming off when it isn’t appropriate,
  • an awareness that the risk referred to here is pretty small and that everything (including stopping taking medication) has both risks and benefits – I shouldn’t take the fact that something has a risk associated with it as an automatic reason not to do it, and
  • an awareness that doctors are told to advise women to stop as there is very little safety information, but this is a precaution, and for some women it can be better for them and their baby to remain on medication.

Despite ALL this, I still walked away from the doctor feeling pretty wobbly. “Maybe I should try again if that’s what the doctor recommends”. It took another discussion with my husband and some more reading and research to help me feel confident in my initial decision again.


Reading and research

That GP said stopping medication was ‘recommended’. A look at the relevant NICE guidelines suggests a rather more subtle approach  – and an informed discussion of the relevant risks and benefits of treatment options.  Perhaps GPs need more support to do this well. Drugs are not clinically tested in pregnant women. We don’t know a lot – even the studies and research that have been done are very small and there are lots of unanswered questions. But my understanding is as follows.

It’s controversial.

Antidepressants are often considered a ‘luxury’ medication like ibuprofen or a sleep aid – a view that seems to stem from a misunderstanding of the nature of mental health problems and the role of medication in treating them.

As far as we have been able to determine, these may be reasons to keep taking them.

And there is a lot of uncertainty about any potential risks of using SSRIs in pregnancy:

Pregnancy, parenting and breastfeeding on Sertraline

Further on in my pregnancy I spoke to a wonderful midwife who said that, based on my history, the most sensible thing I’ve done is continue with the Sertraline. She was right. I am fairly sure it was the best choice for my son, my husband and I.

When Oaklan was born he was monitored in hospital for 48 hours to check for any withdrawal symptoms. He was absolutely fine. Since then, postnatal mental health difficulties have meant I’ve increased my dose to 100mg/day. 16 months later I’m still breastfeeding a healthy toddler, one who is much happier for the fact his mother has appropriate support for her mental health.

Noone can ever be completely certain they have chosen the ‘right’ path for them and their family. But it doesn’t help when we receive simplistic advice that fails to give proper weight to the complexity of our individual experiences and uses the concept of risk to make us feel guilty and disempowered.